Sixty five cases of primary carcinoma of the biliary tree, treated in Taegu Catholic University Hospital from 1983 to 1992, have been reviewed. The average age and the ratio of male to female for gallbladder cancer and bile duct cancer were 62.4,
62.5
years and 1 : 1.2, 1 : 0.9 respectively, Clinical manifestations in order of frequency were abdominal pain(93%), indigestion(67%), jaundice(58%), nausea/vomiting(53%) in bile duct cancer and gallbladder cancer. And also, clinical signs in order
of
frequency were tenderness(62%), jaundice(59%), hopatomegaly(29%) and palpable mass(29%) in bile duct and gallbladder cancer. Tumor locations were found to be in the gallbladder in 28 cases(43%), in the proximal bile duct in 5 cases(23%), in the
middle
bile duct in 3 cases(5%), in the distal bile duct in 15 cases(23%) and in undetermined locations in 4 cases(6%). In the gallbladder cancer, the preoperative diagnosis was made in 13 cases(46.5%), and CT was the most accurate diagnostic
modality(71%
accuracy). In the bile duct cancer, preoperative diagnosis was made in 27 cases(73%), and PTC was the most accurate diagnostic modality(91%). In 28 cases of gallbladder cancer, there were 15 cases(54%) with stone, also, there were 10 cases(27%)
in
37
cases of bile duct cancer. Curative operations were performed in 5 cases(17.8%) in gallbladder cancer and 4 cases(12.5%)in bile duct cancer. The histologic examinations of tumor revealed adenocarcinoma(91%), undifferentiatted carcinoma(7%), and
severe
dysplasia(2%)(clinically malignant). Mean survival time was 5.4 months in gallbladder cancer, 13.2 months in the cases of resection and 5.1 months in the cases of palliative by-pass procedure in bile duct cancer.(Korean J Gastroenterol 1994 ; 26
:
706-715).
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